- Biography
- Research
- Lab Members
- Funded Projects
Professor, Director of Mr. & Mrs. Ko Chi Ming Centre for Parkinson’s Disease Research.
Program Director of BCM & BSc. BIOMED, Teaching & Research Division, Associate Director of Clinical Division.
Expert in Chinese Medicine, Pharmacology of Chinese Medicine, Neurodegenerative Diseases.
Prof. LI Min obtained her Bachelor's degree from the Henan University of Traditional Chinese Medicine (TCM), China, in 1985, her Master's degree in Chinese Medicine at the Guangzhou University of Chinese Medicine, China, in 1988 and her PhD degree in Cardiology at the School of Medicine, Tokai University, Japan, in 2001. Then she joined the School of Chinese Medicine, Hong Kong Baptist University, where she is currently a professor and serves as the Programme Director of BCM, an Associate Director of the Clinical Division and the Director of Mr. and Mrs. Ko Chi Ming Centre for Parkinson's Disease Research. Prof. LI received an Award of the Distinguished Female Chinese Medicine Practitioner by the China Association of Chinese medicine in 2007, School’s Award for Outstanding Performance in Scholarly Work in 2012 and President’s Award for Outstanding Performance in Teaching from Hong Kong Baptist University in 2013. Prof. LI’s clinical specialty is in Chinese medicine treatment of neurodegenerative diseases, including Parkinson's disease (PD), Alzheimer's disease (AD) and vascular dementia (VD), as well as on cardio-cerebrovascular diseases.
Prof. LI’s long-term research interests are:
● Neurodegenerative Diseases Including Parkinson’s disease (PD) and Alzheimer’s Disease (AD).
● Chinese Herbal Medicine for Prevention and Treatment of Neurodegenerative Diseases.
● Development of Molecular Targets for Drug Discovery from TCM for Neurodegenerative Diseases.
Prof. LI’s current research directions are:
● Investigation of the Efficacy and Safety of TCM in the Treatment of Neurodegenerative Diseases including PD and AD based on Randomized Controlled Clinical Trials, as well as the Interaction of TCM and Western Medicine.
● Understanding the Neuroprotective Effects and Underlying Mechanisms of TCM on Neurodegenerative Diseases including PD and AD.
Principal Investigator
Director of Mr. and Mrs. Ko Chi Ming Centre for Parkinson's Disease Research
Program Director of BCM & BSc. BIOMED, Teaching & Research Division
Associate Director of Clinical Division
Chinese Medicine, Neurodegenerative Diseases, Cardiovascular Diseases,
Pharmacology, and Randomized Controlled Clinical Trials
E-mail: limin@hkbu.edu.hk
Research Assistant Professors
Dr. Siva Sundara Kumar DURAIRAJAN (Ph.D.)
Research Assistant Professor
Neurodegenerative diseases, Molecular Pharmacology,
Autophagy & Lysosome Regulation, Neuroprotection, and Chinese Medicine
Email: dsskumar@hkbu.edu.hk
Research Assistant Professor
Neurodegenerative Diseases, Autophagy & Lysosome Regulation, Neuroprotection,
Molecular Pharmacology, and Chinese Medicine
E-mail: s189721@hkbu.edu.hk
Ph.D. Students
Ph.D. Student
Autophagy Regulation, Neurodegenerative Diseases, Neuroprotection, and Chinese Medicine
E-mail: liongphone@gmail.com
Ph.D. Student
Neurodegenerative Diseases, Autophagy Regulation, Neuroprotection, and Molecular Pharmacology
E-mail: leilei.chen2011@gmail.com
Ph.D. Student
Neurodegenerative Diseases, Randomized Controlled Clinical Trials, and Chinese Medicine
E-mail: kyo1212hk@hotmail.com
Research Staff
Dr. Tao-Hua Lan (Ph.D.)
Hong Kong Scholars
Cardiovascular Diseases, Atherosclerosis, Autophagy Regulation, and Chinese Medicine
E-mail: luckyblue1982@126.com
Senior Research Assistant
Autophagy Regulation, Neuroprotection, Molecular Pharmacology, and Chinese Medicine
E-mail: yangchb@hkbu.edu.hk
Dr. Ashock Iyaswamy (Ph.D.)
Senior Research Assistant
Neurodegenerative diseases, Molecular Pharmacology, and Chinese Medicine
E-mail: ashokenviro@gmail.com
Ms. Ying-Yu Huang
Research Assistant
Neurodegenerative diseases, Neuroprotection, and Chinese Medicine Quality Control
E-mail: wongwingyu@hotmail.com
Mr. Sandeep Malampati
Senior Research Assistant
Neurodegenerative diseases, Neuroprotection, and Pharmacology
E-mail: deepu.pharma08@gmail.com
Mr. Sravan Godalakrishna
Research Assistant
Neurodegenerative diseases, Neuroprotection, and Molecular Pharmacology
E-mail: sravangs@gmail.com
Previous Lab Members
Prof. Fu-Long Liao
Prof. Dong Han
Dr. Chi-Ho Chung
Dr. Ming-Qi Zhao
Dr. Chi Zhao
Dr. Li-Xia Xie
Dr. Wan-Fung Kum
Dr. Jia-Hong Lu
Dr. Xing Yu
Mr. Wai-Leuk Fong
Ms. Yan Wang
Mr. Sui-Cheung Man
Mr. Yuan-Chi Lam
Ms. Yu Zeng
Funded Projects
Project 1 | Title: Understanding the molecularmechanisms of Corynoxine B in promoting autophagy and neuroprotection: Targeting HMGB1-Beclin 1 interaction Principal Investigator: Prof. Min Li Funding Body: Hong Kong General Research Fund Project ID: RGC/HKBU-121009/14 Exercise Year: 2015/2016 Approved Project Duration:24 months Project Fund:HK$ 564,833
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Project 2 | Title: Combined Use of ChineseMedicine Decoction (Tianma Gouteng Yin) and Sinemet for the Treatment of Parkinson’s disease: Preclinical Evaluations on Safety and Efficacy Principal Investigator: Prof. Min Li Funding Body: Hong Kong Health and Medical Research Fund Project ID: HMRF/12132091 Exercise Year: 2015/2016 Approved Project Duration:24 months Project Fund:HK$ 999,600 |
Project 3 | Title: Chemical modification of oxindole alkaloids from the Chinese herbal medicine Gouteng for the optimization of anti-Parkinson's disease activity Principal Investigator: Prof. Min Li Funding Body: Hong Kong Innovation and Technology Fund Project ID: ITS/274/12 Exercise Year: 2013/2015 Approved Project Duration: 18 months Project Fund:HK$ 999,925 |
Project 4 | Title: Functional Analysis of Isorhynchophylline in Promoting Autophagy and Protecting Neurons Principal Investigator: Prof. Min Li Funding Body: NSFC / RGC Joint Research Scheme Project ID: N_HKBU213/11 Exercise Year: 2012/2015 Approved Project Duration: 36 months Project Fund:HK$ 794,840 |
Project 5 | Title: Chinese medicine for inflammatory bowel disease and Parkinson's disease: study about the efficacy and its underlying mechanism Principal Investigator: Prof. Min Li Funding Body: Interdisciplinary Research Matching Scheme of HKBU Project ID: HKBUIRMS/12-13/1A Exercise Year: 2012/2015 Approved Project Duration: 36 months Project Fund:HK$ 687,500 |
Project 6 | Title: Natural Neuronal Autophagy Enhancer Schisandrin B: Molecular Targets and Neuroprotective Effects Principal Investigator: Prof. Min Li Funding Body: Faculty Research Grant of HKBU Project ID: HKBU/FRG II/13-14/094 Exercise Year: 2014/2015 Approved Project Duration: 12 months Project Fund:HK$ 120,000 |
Project 7 | Title: Restoration of alpha-synuclein-mediated autophagy deficiency in Parkinson’s disease by natural autophagy inducers Principal Investigator: Prof. Min Li Funding Body: Faculty Research Grant of HKBU Project ID: HKBU/FRG II/12-13/038 Exercise Year: 2013/2014 Approved Project Duration: 12 months Project Fund:HK$ 135,000 |
Project 8 | Title: Development of a mTOR-independent activator of TFEB for the treatment of neurodegenerative diseases Principal Investigator:Prof. Min Li Funding Body: Matching Proof-of-Concept Fund of HKBU Project ID: MPCF-008-2014/2015 Exercise Year: 2014/2015 Approved Project Duration: 12 months Project Fund:HK$ 200,000 |
Project 9 | Title: Preclinical efficacy and safety evaluation of Corynoxine B for the treatment of Parkinson’s disease Principal Investigator: Prof. Min Li Funding Body: Matching Proof-of-Concept Fund of HKBU Project ID: MPCF-004-2012/2013 Exercise Year: 2013/2015 Approved Project Duration: 24 months Project Fund:HK$ 200,000 |
Project 10 | Title: Development of a new drug from Chinese herbal medicine on treatment of Parkinson’s disease Principal Investigator: Prof. Min Li Funding Body: HKBU Project ID: SCM/10-11/03 Exercise Year: 2011/2014 Approved Project Duration: 36 months Project Fund:HK$ 300,000 |
Project 11 | Title: Understanding the role of PI3K/AKT/GSK/β-catenin signaling in the neuroprotective effects of Berberine (BBR) on Aβ-induced tau phosphorylation and toxicity Principal Investigator: Prof. Min Li Funding Body: Faculty Research Grant of HKBU Project ID: HKBU/FRG II/11-12/094 Exercise Year: 2012/2013 Approved Project Duration: 12 months Project Fund:HK$ 120,000 |
Project 12 | Title: Phosphoproteomic study of corynoxine, an alkaloid isolated from Chinese medicine Gouteng, on neuronal cell culture Principal Investigator: Prof. Min Li Funding Body: Faculty Research Grant of HKBU Project ID: HKBU/FRGI/11-12/035 Exercise Year: 2012/2013 Approved Project Duration: 12 months Project Fund:HK$ 40,000 |
Project 13 | Title: 柯诺辛对帕金森病的神经保护作用及诱导神经细胞自噬的磷酸化蛋白调控网络研究 Principal Investigator: Prof. Min Li Funding Body: 深圳市科創委 Project ID: 深圳市未来产业发展专项资金（生命健康类）2014年第四批扶持计划03号 Exercise Year: 2015/2017 Approved Project Duration: Project Fund: RMB50,000 |
Project 14 | Title: An In Vivo Investigation of The Therapeutic Effects of Modified Huang-Lian-Jie-Du-Tang and Its Combination With a Western Drug Principal Investigator: Dr. Durairajan Siva Sundara Kumar Funding Body: Hong Kong Health and Medical Research Fund Project ID: HMRF/11122511 Exercise Year: 2014/2016 Approved Project Duration: 24 months Project Fund:HK$ 904,000 Coordinator: Prof. Li Min |
Project 15 | Title: Structural modification of protopine alkaloid from the Chinese herbal medicine Yanhusuo for the optimization of anti-Alzheimer's disease activity Principal Investigator: Dr. Durairajan Siva Sundara Kumar Funding Body: Hong Kong Innovation and Technology Fund Project ID: ITFS/12132061 Exercise Year: 2014/2015 Approved Project Duration: 18 months Project Fund:HK$ 1,397,250 Coordinator: Prof. Li Min |
Project 16 | Title: Neuropharmacological and Chemical-genetic Approaches to Investigate the Therapeutic Effects of Yuanhu Zhitong Prescription in Treating Alzheimer’s Disease Principal Investigator: Dr. Durairajan Siva Sundara Kumar Funding Body: Hong Kong Innovation and Technology Fund Project ID: HMRF/12132061 Exercise Year: 2015/2016 Approved Project Duration: 24 months Project Fund:HK$ 884,000 Coordinator: Prof. Li Min |
Project 17 | Title: Development of NeuroDefend: A traditional Chinese medicine formula optimized for treating Alzheimer’s disease and other tauopathies. Principal Investigator: Dr. Durairajan Siva Sundara Kumar Funding Body: Hong Kong Innovation and Technology Fund Project ID: ITS/253/14 Exercise Year: 2015/2016 Approved Project Duration: 24 months Project Fund:HK$ 1,400,000 Coordinator: Prof. Li Min |
