2) 

Huo CY, Yang HY, Yu LZ, Fan CL, Quan JY, Deng LE, Yu ZL*, Liu JS*, Cao HH*. Niaoduqing granules inhibits TGF-β1-induced epithelial-mesenchymal transition in human renal tubular epithelial HK-2 cells. TMR Modern Herbal Medicine. 2022,5(3):14.

3) 

Liu YX, Xu BW, Niu XD, Chen YJ, Fu XQ, Wang XQ, Yin CL, Chou JY, Li JK, Wu JY, Bai JX, Wu Y, Li SM, Yu ZL*. Inhibition of Src/STAT3 signaling-mediated angiogenesis is involved in the anti-melanoma effects of dioscin. Pharmacological Research, 2022, 175: 105983.

4) 

鄧筠瑜，童雪，符秀瓊，禹志領. 港澳地區中藥炮製研究概況. 香港中醫雜誌, 2022. 4(17):17.

5) 

Zhang MH, Wang Y, Amin A, Khan MA, Yu ZL*, Liang C*. Network Pharmacology Analysis of Bioactive Components and Mechanisms of Action of Qi Wei Wan Formula for Treating Non-small-cell Lung Carcinoma. Natural Product Communications,  2022;17(10).

6) 

Wu JY, Chen YJ, Fu XQ, Li JK, Chou JY, Yin CL, Bai JX, Wu Y, Wang XQ, Li AS, Wong LY, Yu ZL*. Chrysoeriol suppresses hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes and inhibits JAK2/STAT3 signaling. BMC Complementary Medicine and Therapies, 2022, 22(1): 73.

7) 

Li T, Fu X, Liu B, Wang X, Li J, Zhu P, Niu X, Bai J, Liu Y, Lu X, Yu ZL*. Luteolin binds Src, promotes STAT3 protein ubiquitination and exerts anti-melanoma effects in cell and mouse models. Biochemical Pharmacology, 2022, 200: 115044.

8) 

Wu JY, Xie JH, Chen YJ, Fu XQ, Wang RJ, Deng YY, Wang S, Yu HX, Liang C, Yu ZL*. Amelioration of TPA-induced skin inflammation by the leaf extract of Vernonia amygdalina involves ERK/STAT3 (Ser727) signaling inhibition. Phytomedicine, 2022, 102: 154194.

9) 

Amin A, Hossen MJ, Fu XQ, Chou JY, Wu JY, Wang XQ, Chen YJ, Wu Y, Yin CL, Dou XB, Liang C, Chou GX, Yu ZL*. Inhibition of the Akt/NF-κB pathway is involved in the anti-gastritis effects of an ethanolic extract of the rhizome of Atractylodes macrocephala. Journal of Ethnopharmacology, 2022, 293: 115251.

10) 

Khan SA, Wu Y, Li AS, Fu XQ, Yu ZL*. Network pharmacology and molecular docking-based prediction of active compounds and mechanisms of action of Cnidii Fructus in treating atopic dermatitis. BMC Complementary Medicine and Therapies, 2022, 22(1): 275.

11) 

Pan SY, Nie Q, Tai HC, Song XL, Tong YF, Zhang LJ, Wu XW, Lin ZH, Zhang YY, Ye DY, Zhang Y, Wang XY, Zhu PL, Chu ZS, Yu ZL, Liang C. Tea and tea drinking: China's outstanding contributions to the mankind. Chinese Medicine. 2022,17(1):27.

12) 

Yang W, Zhu L, Lai S, Ding Q, Xu T, Guo R, Dou X, Chai H, Yu ZL, Li S. Cimifugin Ameliorates Lipotoxicity-Induced Hepatocyte Damage and Steatosis through TLR4/p38 MAPK- and SIRT1-Involved Pathways. Oxidative Medicine and Cellular Longevity. 2022,2022:4557532.

13) 

Luo J, Yu ZL, Tovar J, Nilsson A, Xu B. Critical review on anti-obesity effects of phytochemicals through Wnt/β-catenin signaling pathway. Pharmacological Research. 2022,184:106461.

14) 

Wang C, Li S, Liu Q, Qian Q, Fu A, Chen L, Zhang L, Suzaki T, Yu ZL, Dou X. Ectopic accumulation of ceramide in cardiomyocytes modulates alcoholic cardiomyopathy via the TLR4-dependent pathway. Alcoholism, Clinical and Experimental Research. 2022,46(6):1011-1022.

15) 

Liu YX, Xu BW, Niu XD, Chen YJ, Fu XQ, Wang XQ, Yin CL, Chou JY, Li JK, Wu JY, Bai JX, Wu Y, Li SM, Yu ZL*. Inhibition of Src/STAT3 signaling-mediated angiogenesis is involved in the anti-melanoma effects of dioscin. Pharmacol Res. 2022;175:105983.

16) 

Chen YJ, Wu JY, Deng YY, Wu Y, Wang XQ, Li ASM, Wong LY, Fu XQ*, Yu ZL*, Liang C*. Ginsenoside Rg3 in combination with artesunate overcomes sorafenib resistance in hepatoma cell and mouse models. J Ginseng Res. 2022;46(3):418-425.

17) 

Tang MM, Chen YJ, Wu JY, Amin A, Zhou XM, Jin C, Chen GY,. Ethyl acetate extract of the Musa nana flower inhibits osteoclastogenesis and supp Yu ZL resses NF-κB and MAPK pathways. Food Funct. 2021;12(22):11586-11598. 

18) 

Yin C, Fu X, Chou J, Li J, Chen Y, Bai J, Wu J, Wu Y, Wang X, Yu ZL*. A proprietary herbal drug Young Yum Pill ameliorates chronic fatigue syndrome in mice. Phytomedicine. 2021;88:153602.

19) 

Hossen MJ, Amin A, Fu XQ, Chou JY, Wu JY, Wang XQ, Chen YJ, Wu Y, Li J, Yin CL, Liang C, Chou GX, Yu ZL*. The anti-inflammatory effects of an ethanolic extract of the rhizome of Atractylodes lancea, involves Akt/NF-κB signaling pathway inhibition. J Ethnopharmacol. 2021;277:114183.

20) 

Chen YJ, Liu YX, Wu JY, Li CY, Tang MM, Bai L, Fu XQ, Li JK, Chou JY, Yin CL, Wang YP, Bai JX, Wu Y, Wang XQ, Yu ZL*. A two-herb formula inhibits hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes. Sci Rep. 2021;11(1):3850.

21) 

Wang YP, Liu B, Fu XQ, Tong TJ, Yu ZL*. Efficacy and safety of Si-Jun-Zi-Tang-based therapies for functional (non-ulcer) dyspepsia: a meta-analysis of randomized controlled trials. BMC Complement Med Ther. 2021;21(1):11.

22) 

Li JK, Chou JY, Yin CL, Fu XQ, Wu Y, Chen YJ, Bai JX, Wu JY, Liang C, Yu ZL*. A two-herb formula inhibits STAT3 signaling and exerts anti-melanoma effects in cell and animal models. J Ethnopharmacol. 2021;268:113671

23) 

Huo CY, Yang HY, Quan JY, Ning WM, Yu LZ, Fan CL, Deng LE, Yu ZL*, Liu JS*, Cao HH*. Niaoduqing granules inhibits TGF-β1-induced epithelial-mesenchymal transition in human renal tubular epithelial HK-2 cells. Evidence-based Complementary and Alternative Medicine. Under review

24) 

Chan YC, Zhao J, Hu Q, Guo Hui, Liu YX, Wu JY, Zheng ZG, Yu ZL*. Chemical Profile Assessment and Potential Bioactive Component Screening of a Chinese Patent Herbal Drug Yi-Shen-Hua-Shi Granule. Natural Product Communications. 2021;6(16). doi: 10.1177/1934578X211021691. 

25) 

Chen YJ, Wu JY, Deng YY, Wu Y, Wang XQ, Li ASM, Wong LY, Fu XQ*, Yu ZL*, Liang C*. Ginsenoside Rg3 in combination with artesunate overcomes sorafenib resistance in hepatoma cell and mouse models. J Ginseng Res. Accepted. https://doi.org/10.1016/j.jgr.2021.07.002.

26) 

Zhang H, Zhong H, Wang X, Zhang S, Shao X, Hu H, Yu ZL, Cai Z, Chen X, Xia Y. Use of NAD tagSeq II to identify growth-phase dependent alterations in E. coli RNA NAD+-capping. Proc Natl Acad Sci U S A. 2021;118:e2026183118.

27) 

Yin C, Fu X, Chou J, Li J, Chen Y, Bai J, Wu J, Wu Y, Wang X, Yu ZL*. A proprietary herbal drug Young Yum Pill ameliorates chronic fatigue syndrome in mice. Phytomedicine. 2021;88:153602.

28) 

Hossen MJ, Amin A, Fu XQ, Chou JY, Wu JY, Wang XQ, Chen YJ, Wu Y, Li J, Yin CL, Liang C, Chou GX, Yu ZL*. The anti-inflammatory effects of an ethanolic extract of the rhizome of Atractylodes lancea, involves Akt/NF-κB signaling pathway inhibition. J Ethnopharmacol. 2021;277:114183.

29) 

Wang YP, Liu B, Fu XQ, Tong TJ, Yu ZL*. Efficacy and safety of Si-Jun-Zi-Tang-based therapies for functional (non-ulcer) dyspepsia: a meta-analysis of randomized controlled trials. BMC Complement Med Ther. 2021;21(1):11.

30) 

Chen YJ, Liu YX, Wu JY, Li CY, Tang MM, Bai L, Fu XQ, Li JK, Chou JY, Yin CL, Wang YP, Bai JX, Wu Y, Wang XQ, Yu ZL*. A two-herb formula inhibits hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes. Sci Rep. 2021;11(1):3850.

31) 

Wu JY, Chan YC, Guo H, Chen YJ, Liu YX, Yi H, Yu ZL*. Twenty-four-week oral dosing toxicities of Herba Siegesbeckiae in rats. BMC Complement Med Ther. 2020;20(1):341.

32) 

Yang K, Kwan HY, Yu ZL, Tong T. Model selection between the fixed-effects model and the random-effects model in meta-analysis. Stat Interface. 2020; 13:501–510.

33) 

Xia W, Khan I, Li XA, Huang G, Yu ZL, Leong WK, Han R, Ho LT, Wendy Hsiao WL. Adaptogenic flower buds exert cancer preventive effects by enhancing the SCFA-producers, strengthening the epithelial tight junction complex and immune responses. Pharmacol Res. 2020 Jun 3;159:104809.

34) 

Lin X, Liu Y, Ma L, Ma X, Chen Z, Chen H, Si L, Ma X, Yu ZL*, Chen X*. Amelioration of experimental autoimmune encephalomyelitis by Rhodiola rosea, a natural adaptogen. Biomed Pharmacother. 2020;125:109960.

35) 

Zhu PL, Lam DF, Li JK, Fu XQ, Yin CL, Chou JY, Wang YP, Liu YX, Chen YJ, Wu JY, Bai JX, Liang C, Yu ZL*. Gomisin N Exerts Anti-liver Cancer Effects and Regulates PI3K-Akt and mTOR-ULK1 Pathways in Vitro. Biol Pharm Bull, 2020; 43:1267-1271.

36) 

Zeng MN, Li M, Chen YJ, Zhang JK, Cao YG, Zhang BB, Feng WS, Zheng XK, Yu ZL*. A new bisepoxylignan dendranlignan A isolated from Chrysanthemum Flower inhibits the production of inflammatory mediators via the TLR4 pathway in LPS-induced H9c2 cardiomyocytes. Arch Biochem Biophys, 2020; 690:108506.

37) 

Wang YP, Fu XQ, Yin CL, Chou JY, Liu YX, Bai JX, Chen YJ, Wu Y, Wu JY, Wang XQ, Liu B, Yu ZL*. A traditional Chinese medicine formula inhibits tumor growth in mice and regulates the miR-34b/c-Met/β-catenin pathway. J Ethnopharmacol, 2020:113065.

38) 

Amin A, Wu R, Cheung MH, Scott JF, Wang Z, Zhou Z, Liu C, Zhu G, Wong CK, Yu ZL*, Liang C*. An Essential and Cell-Cycle-Dependent ORC Dimerization Cycle Regulates Eukaryotic Chromosomal DNA Replication. Cell Rep. 2020;30(10): 3323-3338.e6.

39) 

Chen YJ, Wu JY, Leung WC, Liu YX, Fu XQ, Zhu JQ, Wu Y, Chou JY, Yin CL, Wang YP, Wang XQ, Bai JX, Wu ZZ, Yu ZL*. An herbal formula inhibits STAT3 signaling and attenuates bone erosion in collagen-induced arthritis rats. Phytomedicine, 2020; 76:153254.

40) 

Xia W, Khan I, Li XA, Huang G, Yu ZL, Leong WK, Han R, Ho LT, Wendy Hsiao WL. Adaptogenic flower buds exert cancer preventive effects by enhancing the SCFA-producers, strengthening the epithelial tight junction complex and immune responses. Pharmacol Res. 2020; 159:104809.

41) 

Su T, Wang YP, Wang XN, Li CY, Zhu PL, Huang YM, Yang ZY, Chen SB, Yu ZL*. The JAK2/STAT3 pathway is involved in the anti-melanoma effects of brevilin A. Life Sci, 2020; 241:117169.

42) 

Fu XQ, Liu B, Wang YP, Li JK, Zhu PL, Li T, Tse K-W, Chou JY, Yin CL, Bai JX, Liu YX, Chen YJ, Yu ZL*. Activation of STAT3 is a key event in TLR4 signaling-mediated melanoma progression. Cell Death Dis, 2020; 11:1-15.

43) 

Liu YX, Xu BW, Chen YJ, Fu XQ, Zhu PL, Bai JX, Chou JY, Yin CL, Li JK, Wang YP, Wu JY, Wu Y, Chan KK, Liang C, Yu ZL*. Inhibiting the Src/STAT3 signaling pathway contributes to the anti‑melanoma mechanisms of dioscin. Oncol Lett, 2020; 19:2508-2514.

44) 

Wu JY, Chen YJ, Bai L, Liu YX, Fu XQ, Zhu PL, Li JK, Chou JY, Yin CL, Wang YP, Bai JX, Wu Y, Yu ZL. Chrysoeriol ameliorates TPA-induced acute skin inflammation in mice and inhibits NF-κB and STAT3 pathways. Phytomedicine. 2020;153173.

45) 

Chen YJ, Bai L, Wu JY, Liu YX, Fu XQ, Zhu PL, Li JK, Wang YP, Chou JY, Yin CL, Bai JX, Wu Y, Yu ZL. A two-herb formula inhibits osteoclastogenesis and suppresses NF-kB and MAPK pathways. J Ethnopharmacol. 2020; 252:112625.

46) 

Lin XL, Liu YY, Ma LL, Ma XM, Chen ZY, Chen H, Si L, Ma XY, Yu ZL*, Chen XH*. Amelioration of experimental autoimmune encephalomyelitis by Rhodiola rosea, a nature adaptogen. Biomed Pharmacother. 2020;15:109960.

47) 

Ahmad I, Fakhri S, Khan H, Jeandet P, Aschner M, Yu ZL*. Targeting cell cycle by β-carboline alkaloids in vitro: Novel therapeutic prospects for the treatment of cancer. Chem Biol Interact. 2020;330:10922.

48) 

Fu XQ, Liu B, Wang YP, Li JK, Zhu PL, Li T, Tse KW, Chou JY, Yin CL, Bai JX, Liu YX, Chen YJ, Yu ZL*. Activation of STAT3 is a key event in TLR4 signaling-mediated melanoma progression. Cell Death Dis. 2020;11(4):246. 

49) 

Liu YX, Xu BW, Chen YJ, Fu XQ, Zhu PL, Bai JX, Chou JY, Yin CL, Li JK, Wang YP, Wu JY, Wu Y, Chan KK, Liang C, Yu ZL*. Inhibiting the Src/STAT3 signaling pathway contributes to the anti-melanoma mechanisms of dioscin. Oncol Lett. 2020;19(3):2508-2514.

50) 

Zhu PL, Lam DF, Li JK, Fu XQ, Yin CL, Chou JY, Wang YP, Liu YX, Chen YJ, Wu JY, Wu Y, Bai JX, Liang C, Yu ZL*. Gomisin N Exerts Anti-liver Cancer Effects and Regulates PI3K-Akt and mTOR-ULK1 Pathways in Vitro. Biol Pharm Bull. 2020;43(8):1267-1271.

51) 

Wang YP, Fu XQ, Yin CL, Chou JY, Liu YX, Bai JX, Chen YJ, Wu Y, Wu JY, Wang XQ, Liu B, Yu ZL*. A traditional Chinese medicine formula inhibits tumor growth in mice and regulates the miR-34b/c-Met/β-catenin pathway. J Ethnopharmacol. 2020;260:113065.

52) 

Wu JY, Chen YJ, Bai L, Liu YX, Fu XQ, Zhu PL, Li JK, Chou JY, Yin CL, Wang YP, Bai JX, Wu Y, Wu ZZ, Yu ZL*. Chrysoeriol ameliorates TPA-induced acute skin inflammation in mice and inhibits NF-κB and STAT3 pathways. Phytomedicine. 2020;68:153173. 

53) 

Chen YJ, Wu JY, Leung WC, Liu YX, Fu XQ, Zhu JQ, Wu Y, Chou JY, Yin CL, Wang YP, Wang XQ, Bai JX, Wu ZZ, Yu ZL*. An herbal formula inhibits STAT3 signaling and attenuates bone erosion in collagen-induced arthritis rats. Phytomedicine. 2020;76:153254. 

54) 

Su T, Wang YP, Wang XN, Li CY, Zhu PL, Huang YM, Yang ZY, Chen SB, Yu ZL. The JAK2/STAT3 pathway is involved in the anti-melanoma effects of brevilin A. Life Sci. 2020;241:117169. 

55) 

Zhao J, Chan YC, He B, Duan TT, Yu ZL*. A patent herbal drug Yi-Shen-Hua-Shi granule ameliorates C-BSA-induced chronic glomerulonephritis and inhabits TGFβ signaling in rats. J Ethnopharmacol, 2019; 236:258-262.

56) 

Chen YJ, Zhu JQ, Fu XQ, Su T, Li T, Guo H, Zhu PL, Lee SK, Yu H, Tse AK, Yu ZL. Ribosome-Inactivating Protein α-Momorcharin Derived from Edible Plant Momordica charantia Induces Inflammatory Responses by Activating the NF-kappaB and JNK Pathways.Toxins (Basel). 2019;11(12). pii: E694.

57) 

Zhu P, Li J, Fu X, Yu ZL. Schisandra fruits for the management of drug-induced liver injury in China: A review.Phytomedicine. 2019;59:152760.

58) 

Liu YX, Bai JX, Li T, Fu XQ, Chen YJ, Zhu PL, Chou JY, Yin CL, Li JK, Wang YP, Wu JY, Yu ZL. MiR-let-7a/f-CCR7 signaling is involved in the anti-metastatic effects of an herbal formula comprising Sophorae Flos and Lonicerae Japonicae Flos in melanoma. Phytomedicine. 2019;64:153084.

59) 

Liu YX, Bai JX, Li T, Fu XQ, Guo H, Zhu PL, Chan YC, Chou JY, Yin CL, Li JK, Wang YP, Chen YJ, Yu ZL. A TCM formula comprising Sophorae Flos and Lonicerae Japonicae Flos alters compositions of immune cells and molecules of the STAT3 pathway in melanoma microenvironment. Pharmacol Res. 2019;142:115-126. [Best Research Article Award].

60) 

Hossen MJ, Chou JY, Li SM, Fu XQ, Yin C, Guo H, Amin A, Chou GX, Yu ZL. An ethanol extract of the rhizome of Atractylodes chinensis exerts anti-gastritis activities and inhibits Akt/NF-κB signaling. J Ethnopharmacol. 2019 Jan 10;228:18-25.

61) 

Zhu PL, Li JK, Fu XQ, Yu ZL. Schisandra fruits for the management of drug-induced liver injury in China: A review. Phytomedicine. 2019;59:152760.

62) 

Yin CL, Hossen MJ, Tse AK, Su T, Fu XQ, Li T, Guo H, Zhu PL, Li JK, Chou JY, Wang YP, Yu ZL. Young Yum Pill inhibits inflammatory mediators and NF-κB signaling in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Traditional Chinese Medicine. 2019; 39(5):624-631.

63) 

Liu YX, Bai JX, Li T, Fu XQ, Chen YJ, Zhu PL, Chou JY, Yin CL, Li JK, Wang YP, Wu JY, Yu ZL*. MiR-let-7a/f-CCR7 signaling is involved in the anti-metastatic effects of an herbal formula comprising Sophorae Flos and Lonicerae Japonicae Flos in melanoma. Phytomedicine. 2019;64:153084.  

64) 

Zhu PL, Zheng ZY, Fu XQ, Li JK, Yin CL, Chou JY, Wang YP, Liu YX, Chen YJ, Bai JX, Wu JY, Chen SB, Yu ZL*. Arnicolide D exerts anti-melanoma effects and inhibits the NF-kB pathway. Phytomedicine. 2019;64:153065.

65) 

Zhao J, Chan YC, He B, Duan TT, Yu ZL*. A patent herbal drug Yi-Shen-Hua-Shi granule ameliorates C-BSA-induced chronic glomerulonephritis and inhabits TGFβ signaling in rats. J Ethnopharmacol. 2019 Mar 2; 236: 258-262.

66) 

Liu YX, Bai JX, Li T, Fu XQ, Guo H, Zhu PL, Chan YC, Chou JY, Yin CL, Li JK, Wang YP, Chen YJ, Yu ZL*. A TCM formula comprising Sophorae Flos and Lonicerae Japonicae Flos alters compositions of immune cells and molecules of the STAT3 pathway in melanoma microenvironment. Pharmacol Res. 2019; 142: 115-126.

67) 

Liu JS, Huo CY, Cao HH, Fan CL, Hu JY, Deng LJ, Lu ZB, Yang HY, Yu LZ, Mo ZX, Yu ZL*. Aloperine induces apoptosis and G2/M cell cycle arrest in hepatocellular carcinoma cells through the PI3K/Akt signaling pathway. Phytomedicine. 2019 Jan 28;61:152843.

68) 

Liu JS, Deng LJ, Tian HY, Ruan ZX, Cao HH, Ye WC, Zhang DM, Yu ZL*. Anti-tumor effects and 3D-quantitative structure-activity relationship analysis of bufadienolides from toad venom. Fitoterapia. 2019 Apr;134:362-371.

69) 

Chen J, Jayachandran M, Zhang W, Chen L, Du B, Yu Z*, Xu B*. Schisandra fruits for the management of drug-induced liver injury in China: A review. Phytomedicine. 2019 Jun;59:152760.

70) 

Chen J, Jayachandran M, Xu B, Yu Z*. Sea bass (Lateolabrax maculatus) accelerates wound healing: A transition from inflammation to proliferation. J Ethnopharmacol. 2019 May 23;236:263-276.

71) 

Hossen MJ, Chou JY, Li SM, Fu XQ, Yin C, Guo H, Amin A, Chou GX, Yu ZL*. An ethanol extract of the rhizome of Atractylodes chinensis exerts anti-gastritis activities and inhibits Akt/NF-κB signaling. J Ethnopharmacol. 2019; 228: 18-25.

72) 

Zhu PL, Li JK, Fu XQ, Yu ZL*. Schisandra fruits for the management of drug-induced liver injury in China: A review. Phytomedicine. 2019; 59: 152760.

73) 

Yin CL, Hossen MJ, Tse AK, Su T, Fu XQ, Li T, Guo H, Zhu PL, Li JK, Chou JY, Wang YP, Yu ZL*. Young Yum Pill inhibits inflammatory mediators and NF-κB signaling in lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Traditional Chinese Medicine.Accepted.

74) 

Zhu PL, Fu XQ, Li JK, Tse AK, Guo H, Yin CL, Chou JY, Wang YP, Liu YX, Chen YJ, Hossen MJ, Zhang Y, Pan SY, Zhao ZJ, Yu ZL. Antrodia camphorata Mycelia Exert Anti-liver Cancer Effects and Inhibit STAT3 Signaling in vitro and in vivo. Front Pharmacol. 2018 Dec 17;9:1449.

75) 

Zhang Y, Guo H, Cheng BC, Su T, Fu XQ, Li T, Zhu PL, Tse KW, Pan SY, Yu ZL. Dingchuan Tang essential oil inhibits the production of inflammatory mediators via suppressing the IRAK/NF-κB, IRAK/AP-1 and TBK1/IRF3 pathways in LPS-stimulated RAW264.7 cells. Drug Des Dev Ther. 2018;12:2731–2748.

76) 

Guo H, Zhang Y, Cheng BC, Fu XQ, Zhu PL, Chen JL, Chan YC, Yin CL, Wang YP, Hossen MJ, Amin A, Tse AK, Yu ZL. An ethanolic extract of the aerial part of Siegesbeckia orientalis L. inhibits the production of inflammatory mediators regulated by AP-1, NF-κB and IRF3 in LPS-stimulated RAW 264.7 cells. Biosci Trends. 2018; 12:330-337.

77) 

Hossen MJ, Chou JY, Li SM, Fu XQ, Yin C, Guo H, Amin A, Chou GX, Yu ZL. An ethanol extract of the rhizome of Atractylodes chinensis exerts anti-gastritis activities and inhibits Akt/NF-κB signaling. J Ethnopharmacol. 2018; 228:18-25.

78) 

Guo H, Zhang Y, Cheng BC, Lau MY, Fu XQ, Li T, Su T, Zhu PL, Chan YC, Tse AK, Yi T, Chen HB, Yu ZL. Comparison of the chemical profiles and inflammatory mediator-inhibitory effects of three Siegesbeckia herbs used as Herba Siegesbeckiae (Xixiancao).BMC Complement Altern Med. 2018; 18:141.

79) 

Zhu PL, Fu XQ, Li JK, Tse KW, Guo H, Yin CL, Chou JY, Wang YP,  Liu YX, Chen YJ, Hossen MJ, Zhang Y, Pan SY, Zhao ZJ, Yu ZL*. Antrodia camphorata mycelia exert anti-liver cancer effects and inhibit STAT3 signaling in vitro and in vivo. Front Pharmacol. 2018; 9: 1449.

80) 

Zhang Y, Guo H, Cheng BC, Su T, Fu XQ, Li T, Zhu PL, Tse KW, Pan SY, Yu ZL*. Dingchuan Tang essential oil inhibits the production of inflammatory mediators via suppressing the IRAK/NF-κB, IRAK/AP-1 and TBK1/IRF3 pathways in LPS-stimulated RAW264.7 cells. DrugDes Dev Ther. 2018:12 2731–2748.

81) 

Guo H, Zhang Y, Cheng BC, Fu XQ, Zhu PL, Chen JL, Chan YC, Yin CL, Wang YP, Hossen MJ, Amin A, Tse AK, Yu ZL*. An ethanolic extract of the aerial part of Siegesbeckia orientalis L. inhibits the production of inflammatory mediators regulated by AP-1, NF-κB and IRF3 in LPS-stimulated RAW 264.7 cells. Biosci Trends. 2018; 12(3): 330-337.

82) 

Guo H, Zhang Y, Cheng BC, Lau MY, Fu XQ, Li T, Su T, Zhu PL, Chan YC, Tse AK, Yi T, Chen HB, Yu ZL*. Comparison of the chemical profiles and inflammatory mediator-inhibitory effects of three Siegesbeckia herbs used as Herba Siegesbeckiae (Xixiancao).BMC Complement Altern Med. 2018 May 2; 18(1): 141.

83) 

Fu XQ, Chou JY, Li T, Zhu PL, Li JK, Yin CL, Su T, Guo H, Lee KW, Hossen MJ, Chou GX, Yu ZL*. The JAK2/STAT3 pathway is involved in the anti-melanoma effects of atractylenolide I. Exp Dermatol. 2018 Feb; 27(2): 201-204.

84) 

Su T, Wang XN, Li CY, Bai JX, Cheng BCY, Fu XQ, Li T, Yu ZL. In vitro anti-colorectal cancer effects of an Ampelopsis Radix extract. J Tradic Chin Med. Accepted.

85) 

Niu XD, Yu YD, Guo H, Yang YN, Wang GZ, Sun L, Gao YW, Yu ZL, Wang HS. Molecular modeling reveals the inhibition mechanism and binding mode of ursolic acid to TLR4-MD2. Computational and Theoretical Chemistry. 2017 Nov. doi: 10.1016/j.comptc.2017.11.016

86) 

盧子濱, 范春林, 周紅玲, 禹志領, 余林中, 劉俊珊. 苦豆堿對小鼠的急性毒性研究. 天然產物研究與開發. 2017; 29: 821-825.

87) 

Fu XQ, Chou JY, Li T, Zhu PL, Li JK, Yin CL, Su T, Guo H, Lee KW, Hossen MJ, Chou GX, Yu ZL. The JAK2/STAT3 pathway is involved in the anti-melanoma effects of atractylenolide I. Exp Dermatol. 2017 Oct 27. doi: 10.1111/exd.13454.

88) 

Liu B, Fu XQ, Li T, Su T, Guo H, Zhu PL, Tse AK, Liu SM, Yu ZL. Computational and experimental prediction of molecules involved in the anti-melanoma action of berberine. J Ethnopharmacol. 2017 Aug 17; 208: 225-235.

89) 

Kwan HY, Wu J, Su T, Chao XJ, Yu H, Liu B, Fu X, Tse AKW, Chan CL, Fong WF, Yu ZL. Schisandrin B regulates lipid metabolism in subcutaneous adipocytes. Sci Rep. 2017 Aug 31;7(1): 10266.

90) 

Chen L, Teng H, Jia Z, Battino M, Miron A, Yu Z, Cao H, Xiao J. Intracellular signaling pathways of inflammation modulated by dietary flavonoids: The most recent evidence. Crit Rev Food Sci Nutr. 2017 Jul 6; 1-17. doi: 10.1080/10408398.2017.1345853.

91) 

楊春雨, 曹暉, 王孝濤, 塗家生, 錢忠直, 禹志領, 尚悅, 張保獻. 我國炮製用輔料標準現狀研究及工作建議. 中國中藥雜誌, 2017; 42(7): 1041-1046.

92) 

Li T, Fu XQ, Tse AK, Guo H, Lee KW, Liu B, Su T, Wang XY, Yu ZL. Inhibiting STAT3 signaling is involved in the anti-melanoma effects of a herbal formula comprising Sophorae Flos and Lonicerae Japonicae Flos. Sci Rep. 2017 Jun 8; 7(1): 3097.

93) 

Kwan HY, Wu J, Su T, Chao XJ, Liu B, Fu XQ, Chan CL, Lau RHY, Tse AKW, Han QB, Fong WF, Yu ZL. Cinnamon induces browning in subcutaneous adipocytes. Sci Rep. 2017 May 26; 7(1): 2447.

94) 

Tse AK, Chen YJ, Fu XQ, Su T, Li T, Guo H, Zhu PL, Kwan HY, Cheng BC, Cao HH, Lee SK, Fong WF, Yu ZL. Sensitization of melanoma cells to alkylating agent-induced DNA damage and cell death via orchestrating oxidative stress and IKKβ inhibition. Redox Biol. 2017 Apr; 11: 562-576.

95) 

Su T, Bai JX, Chen YJ, Wang XN, Fu XQ, Li T, Guo H, Zhu PL, Wang Y, Yu ZL. An Ethanolic Extract of Ampelopsis Radix Exerts Anti-colorectal Cancer Effects and Potently Inhibits STAT3 Signaling In Vitro. Front Pharmacol. 2017 Apr 28; 8: 227.

96) 

Zhang Y, Zhao J, Zhou SF, Yu ZL, Wang XY, Zhu PL, Chu ZS, Pan SY, Xie M, Ko KM. Biochemical mechanism underlying hypertriglyceridemia and hepatic steatosis/hepatomegaly induced by acute schisandrin B treatment in mice. Lipids Health Dis. 2017 Jan 13; 16(1): 8.

97) 

Luo M, Liu Q, He M, Yu ZL, Pi R, Li M, Yang X, Wang S, Liu A. Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signaling pathway in human glioma cells. J Cell Mol Med. 2017 Jan; 21(1): 46-57.

98) 

盧子濱, 范春林, 周紅玲, 禹志領, 陳衛民, 余林中, 劉俊珊. 苦豆子化學成分及藥理作用研究進展. 天然產物研究與開發. 2017; 29(增刊1): 202-206.

99) 

Su T, Wang XN, Li CY, Bai JX, Cheng BCY, Fu XQ, Li T, Yu ZL*. In vitro anti-colorectal cancer effects of an Ampelopsis Radix extract. J Tradic Chin Med. Accepted.

100) 

Niu XD, Yu YD, Guo H, Yang YN, Wang GZ, Sun L, Gao YW, Yu ZL*, Wanga HS*. Molecular modeling reveals the inhibition mechanism and binding mode of ursolic acid to TLR4-MD2. Comput Theor Chem. 2017 Nov. doi: 10.1016/j.comptc.2017.11.016. 

101) 

Kwan HY, Wu J, Su T, Chao XJ, Yu H, Liu B, Fu X, Tse AKW, Chan CL, Fong WF, Yu ZL*. Schisandrin B regulates lipid metabolism in subcutaneous adipocytes. Sci Rep. 2017 Aug 31; 7(1): 10266.

102) 

Liu B, Fu XQ, Li T, Su T, Guo H, Zhu PL, Tse AK, Liu SM*, Yu ZL*. Computational and experimental prediction of molecules involved in the anti-melanoma action of berberine. J Ethnopharmacol. 2017; 208: 225-235.

103) 

Chen L, Teng H, Jia Z, Battino M, Miron A, Yu ZL*, Cao H, Xiao J* Intracellular signaling pathways of inflammation modulated by dietary flavonoids: The most recent evidence. Crit Rev Food Sci Nutr. 2017:0. doi: 10.1080/10408398.2017.1345853.

104) 

Li T, Fu X, Tse AK, Guo H, Lee KW, Liu B, Su T, Wang X, Yu ZL. Inhibiting STAT3 signaling is involved in the anti-melanoma effects of a herbal formula comprising Sophorae Flos and Lonicerae Japonicae Flos. Sci Rep. 2017 Jun 8; 7(1): 3097.

105) 

Kwan HY, Wu J, Su T, Chao XJ, Liu B, Fu X, Chan CL, Lau RHY, Tse AKW, Han QB, Fong WF, Yu ZL. Cinnamon induces browning in subcutaneous adipocytes. Sci Rep. 2017 May 26; 7(1): 2447

106) 

Su T, Bai JX, Chen YJ, Wang XN, Fu XQ, Li T, Guo H, Zhu PL, Wang Y, Yu ZL*. An Ethanolic Extract of Ampelopsis Radix Exerts Anti-colorectal Cancer Effects and Potently Inhibits STAT3 Signaling In Vitro. Front Pharmacol. 2017 Apr 28;8:227.

107) 

Tse AKW*, Chen YJ, Fu XQ, Su T, Li T, Guo H, Zhu PL, Kwan HY, Cheng BCY, Cao HH, Lee SKW, Fong WF, Yu ZL*. Sensitization of melanoma cells to alkylating agent-induced DNA damage and cell death via orchestrating oxidative stress and IKKβ inhibition. Redox Biol. 2017 Apr; 11: 562-576.

108) 

Kwan HY*, Chao XJ, Su T, Fu XQ, Tse AK, Fong WF, Yu ZL*. The anti-cancer and anti-obesity effects of Mediterranean diet. Crit Rev Food Sci Nutr. 2017; 57(1):82-94.

109) 

Cheng BCY, Fu XQ, Guo H, Li T, Wu ZZ, Chan, K, Yu ZL. The genus Rosa and arthritis: Overview on pharmacological perspectives. Pharmacol Res. 2016; 114: 219-234.

110) 

Sun XG, Lin XC, Diao JX, Yu ZL, Li K. Pi (Spleen)-deficiency syndrome in tumor microenvironment is the pivotal pathogenesis of colorectal cancer immune escape. Chin J Integr Med. 2016 Oct; 22(10):789-794.

111) 

Su T, Tan Y, Tsui MS, Yi H, Fu XQ, Li T, Chan CL, Guo H, Li YX, Zhu PL, Tse AK, Cao H, Lu AP, Yu ZL. Metabolomics reveals the mechanisms for the cardiotoxicity of Pinelliae Rhizoma and the toxicity-reducing effect of processing. Sci Rep. 2016 Oct 4; 6: 34692.

112) 

Su T, Zhang WW, Zhang YM, Cheng BC, Fu XQ, Li T, Guo H, Li YX, Zhu PL, Cao H, Yu ZL. Standardization of the manufacturing procedure for Pinelliae Rhizoma Praeparatum cum Zingibere et Alumine. J Ethnopharmacol. 2016 Dec 4; 193:663-669.

113) 

Du J, Yan Cheng BC, Fu XQ, Su T, Li T, Guo H, Li SM, Wu JF, Yu H, Huang WH, Cao H, Yu ZL. In vitro assays suggest Shenqi Fuzheng Injection has the potential to alter melanoma immune microenvironment. J Ethnopharmacol. 2016 Dec 24; 194: 15-19.

114) 

Du J, Wu JF, Fu XQ, Tse KW, Li T, Su T, Yu ZL. Icairiside II Overcomes TRAIL Resistance of Melanoma Cells through ROS-Mediated Downregulation of STAT3/cFLIP signalling. Oncotarget. 2016 Aug 9; 7(32): 52218–52229.

115) 

Wu JF, Du J, Fu XQ, Liu B, Li T, Su T, Tse AKW, Yu ZL. Iciartin, a novel FASN inhibitor, exerts anti-melanoma activities through IGF-1R/STAT3 signaling. Oncotarget. 2016 Aug 9; 7(32): 51251-51269.

116) 

Hossen MJ, Uddin MB, Ahmed SS, Yu ZL, Cho JY. Traditional Medicine/Plants for the Treatment of Reproductive Disorders in Asia Nations. Pak Vet J. 2016; 36: 127-133.

117) 

Ma XQ, Li SM, Chan CL, Su T, Cheng BCY, Li WD, Fong WF, Yu ZL. Inference of sulfur fumigation on volatile oil constitutnets of Codonopsis Radix (Dangshen) by GC-MS method. Afr J Tradit Complem. 2016; 13: 197-202.

118) 

Ma XQ, Li SM, Chan CL, Su T, Li WD, Cao H, Fong WF, Yu ZL. Influence of sulfur fumigation on glycoside profile in the dried root of Platycodon grandiflorum (Jiegeng). Chin Med. 2016 Jul 6; 11: 32.

119) 

Yi T, Fang JY, Zhu L, Tang YN, Ji H, Zhang YZ, Yu JC, Zhang XJ, Yu ZL, Zhao ZZ, Chen HB. The variation in the major constituents of the dried rhizome of Ligusticum chuanxiong (Chuanxiong) after herbal processing. Chin Med. 2016; 11: 26.

120) 

Cao HH, Chu JH, Kwan HY, Su T, Yu H, Cheng CY, Fu XQ, Guo H, Li T, Tse AKW, Chou GX, Mo HB, Yu ZL. Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated antimetastatic effect in melanoma. Sci Rep. 2016 Feb 25; 6: 21731.

121) 

Cheng CY, Yu H, Guo H, Su T, Fu XQ, Li T, Cao HH, Tse KW, Zheng-Zhi Wu ZZ, Kwan HY, Yu ZL. A herbal formula comprising Rosae Multiflorae Fructus and Lonicerae Japonicae Flos attenuates collagen-induced arthritis and inhibits TLR4 signalling.in rats. Sci Rep. 2016 Feb 10; 6: 20042.

122) 

Wong VKW, Dong H, Liang X, Bai LP, Jiang ZH, Guo Y, Kong T, Wang R, Kam RKT, Law BYK, Hsiao WL, Chan KM, Wang JR, Chan RWK, Guo JR, Zhang W, Yen FG, Zhou H, Leung ELH, Yu ZL, Liu L. Rh2E2, a Novel Metabolic Suppressor, Specifically Inhibits Energy-based Metabolism of Tumor Cells. Oncotarget. 2016 Mar 1; 7(9): 9907-9924.

123) 

Su T, Cheng CY, Fu XQ, Li T, Guo H, Cao HH, Kwan HY,  Tse KW, Yu H, Cao H, Yu ZL. Comparison of the toxicities, activities and chemical profiles of raw and processed Xanthii Fructus. BMC Complement Altern Med. 2016; 16(1): 24.

124) 

Shu X, Jiang XW, Cheng CY, Chen GY, Yu ZL. Ultra-performance liquid chromatography-quadrupole/time-of-flight mass spectrometry analysis of the impact of processing on toxic components of Kansui Radix. BMC Complement Altern Med. 2016 Feb 24; 16:73.

125) 

Liu B, Zhang JZ, Liu WH, Liu NN, Fu XQ, Kwan HY, Liu SJ, Liu BR, Zhang SW, Yu ZL, Liu SM. Calycosin inhibits oxidative stress-induced cardiomyocyte apoptosis via activating estrogen receptor-α/β. Bioorg Med Chem Lett. 2016; 26: 181-185.

126) 

Kwan HY, Chao XJ, Su T, Fu XQ, Tse AK, Fong WF, Yu ZL. The anti-cancer and anti-obesity effects of Mediterranean diet. Crit Rev Food Sci Nutr. 2015 Apr 1; 89-94. doi:10.1080/10408398.2013.852510.

127) 

Cao HH, Cheng CY, Su T, Fu XQ, Guo H, Li T, Tse AK, Kwan HY, Yu H, Yu ZL. Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion. Mol Cancer. 2015 May 14; 14: 103.

128) 

Cheng BCY, Yu H, Su T, Fu XQ, Guo H, Ting LI, Cao HH, Tse KW, Kwan HY, Yu ZL. A herbal formula comprising Rosae Multiflorae Fructus and Lonicerae Japonicae Flos inhibits the production of inflammatory mediators and the IRAK-1/TAK1 and TBK1/IRF3 pathways in RAW 264.7 and THP-1 cells. J Ethnopharmacol. 2015; 174: 195-199.

129) 

Kwan HY, Niu X, Dai W, Tong T, Chao X, Su T, Chan CL, Lee KC, Fu X, Yi H, Yu H, Li T, Tse KW, Fong WF, Pan SY, Lu A, Yu ZL. Lipidomic-based investigation into the regulatory effect of Schisandrin B on palmitic acid level in non-alcoholic steatotic livers. Sci Rep. 2015; 5: 9114.

130) 

Kwan HY, Chao XJ, Su T, Fu XQ, Liu Bin, Tse KW, Fong WF, Yu ZL. Dietary Lipids and Adipocytes: Potential Therapeutic Targets in Cancers. J Nutr Biochem. 2015; 26: 303-311.

131) 

Zhu PL, Pan SY, Zhou SF, Zhang Y, Wang XY, Sun Nan, Chu ZS, Yu ZL, Ko KM. Effects of combined dietary supplementation with fenofibrate and Schisandrae Fructus pulp on lipid, glucose and liver function in normal and hypercholesterolemic mice. Drug Des Devel Ther. 2015; 9: 923–935.

132) 

Ye Y, Chao XJ, Wu JF, Cheng BC, Su T, Fu XQ, Li T, Guo H, Tse AK, Kwan HY, Du J, Chou GX, Yu ZL. ERK/GSK3β signaling is involved in atractylenolide I-induced apoptosis and cell cycle arrest in melanoma cells. Oncol Rep. 2015; 34: 1543-1548.

133) 

Chu ZS, Yu ZL(co-first author), Pan SY, Jia ZH, Wang XY, Zhang Y, Zhu PL, Wang XJ, Ko KM. A comparative study between Wuweizi seed and its post-ethanol extraction residue in normal and hypercholesterolemic mice. Lipids Health Dis. 2015; 14: 93.

134) 

Guo YQ, Sun HY, Chan CO, Liu BB, Wu JH, Chan SW, Mok DKW, Tse AKW, Yu ZL, Chen SB. Centipeda minima (Ebushicao) extract inhibits PI3K-Akt-mTOR signaling in nasopharyngeal carcinoma CNE-1 cells. Chin Med. 2015; 10: 26.

135) 

Wei Y, Wang X, Yu ZL, Zhou W, Wang L, Qin F, Wang C, Hou L. Efficacy and Mechanism of Action of Yiru Tiaojing Granule Against Hyperprolactinemia In Vitro and In Vivo. Planta Med. 2015; 81: 1255-1262.

136) 

Kwan HY, Su T, Fu XQ, Tse AK, Fong WF, Yu ZL. Herbal remedies against adipogenesis. J Alt Med Res. 2015; 1: 1-7.

137) 

Cheng CY, Guo H, Su T, Fu XQ, Li T, Yu ZL. In vivo and in vitro anti-arthritic efficacy of a herbal formula consisting of Rosae Multiflorae Fructus and Lonicerae Japonicae Flos. Chin J Pharmacol Toxicol. 2015; 29(S1): 59-60.

138) 

Chik WI, Zhu L, Fan LL, Yi T, Zhu GY, Gou XJ, Tang YN, Xu J, Yeung WP, Zhao ZZ, Yu ZL, Chen HB. Saussurea involucrata: A review of the botany, phytochemistry and ethnopharmacology of a rare traditional herbal medicine. J Ethnopharmacol. 2015; 172: 44-60.

139) 

Zhang Y, Zhou ZW, Jin H, Hu C, He ZX, Yu ZL, Ko KM, Yang T, Zhang X, Pan SY, Zhou SF. Schisandrin B inhibits cell growth and induces cellular apoptosis and autophagy in mouse hepatocytes and macrophages: implications for its hepatotoxicity. Drug Des Devel Ther. 2015; 9: 2001-2027.

140) 

Pan SY, Gao SH, Zhou SF, Dong HG, Tang MK, Yu ZL, Ko KM. New perspectives on dietary-derived treatments and food safety ― Antinomy in a new era. Crit Rev Food Sci Nutr. 2015; 55(13): 1836-1859.

141) 

Kwan HY, Fu   X, Liu B, Chao X, Chan CL, Cao HH, Su T, Tse AK, Fong WF Yu ZL (Corresponding Author).   Subcutaneous adipocytes promote melanoma cell growth by activating Akt   signaling pathway: role of palmitic acid. J Biol Chem. 2014;289(44):30525-37.

142) 

Cao HH, Tse   AK, Kwan HY, Yu H, Cheng CY, Su T, Fong WF, Yu ZL (Corresponding Author).   Quercetin exerts anti-melanoma activities and inhibits STAT3 signaling. Biochem   Pharmacol. 2014;87(3):424-34.

143) 

Tse AW, Cao   HH, Cheng CY, Kwan HY, Yu H, Fong WF, Yu ZL (Corresponding Author).   Indomethacin Sensitizes TRAIL-Resistant Melanoma cells to TRAIL-induced   Apoptosis through ROS-mediated Up-regulation of Death Receptor 5 and   Down-regulation of Survivin. J Invest Dermatol. 2014;134(5):1397-407.

144) 

Kwan HY, Chao   XJ, Su T, Fu XQ, Tse AK, Fong WF, Yu ZL (Corresponding Author). The anti-cancer and   anti-obesity effects of Mediterranean diet. Crit Rev Food Sci Nutr. 2014; doi: 10.1080/10408398.2013.852510.

145) 

Fu XQ, Chou GX,   Kwan HY, Tse KW, Zhao LH, Yuen TK, Cao HH, Yu H, Chao XJ, Su T, Cheng CY, Sun   XG, Yu ZL (Corresponding Author).   Inhibition of STAT3 signaling contributes to the anti-melanoma action   of atractylenolide II. Exp Dermatol.   2014;23(11):855-7.

146) 

Su T, Yu H, Kwan HY, Ma XQ, Cao HH,   Cheng CY, Leung AK, Chan CL, Li WD, Cao H, Fong WF, Yu ZL (Corresponding Author). Comparisons   of the chemical profiles, cytotoxicities and anti-inflammatory effects of raw   and rice wine-processed Herba Siegesbeckiae. J Ethnopharmacol. 2014;156:365-9.

147) 

Wang H, Ye Y, Yu ZL (Corresponding Author).   Proteomic and functional analyses demonstrate the involvement of oxidative   stress in the anticancer activities of oridonin in HepG2 cells. Oncol Rep. 2014;31(5):2165-72.

148) 

Chao XJ, Chen ZW, Liu AM, He XX, Wang   SG, Wang YT, Liu PQ, Ramassamy C, Mak SH, Cui W, Kong AN, Yu ZL, Han YF, Pi RB. Effect of   tacrine-3-caffeic acid, a novel multifunctional anti-Alzheimer's dimer,   against oxidative-stress-induced cell death in HT22 hippocampal neurons:   involvement of Nrf2/HO-1 pathway. CNS   Neurosci Ther. 2014;20(9):840-50.

149) 

Zhang Y, Pan SY, Zhou SF, Wang XY,   Sun N, Zhu PL, Chu ZS, Yu ZL, Ko   KM. Time and dose relationships between schisandrin B- and schisandrae   fructus oil-induced hepatotoxicity and the associated elevations in hepatic   and serum triglyceride levels in mice. Drug   Des Devel Ther. 2014;8:1429-39.

150) 

Pan SY, Litscher G, Chan K, Yu ZL, Chen HQ, Ko KM. Traditional   medicines in the world: where to go next? Evid Based Complement Alternat Med. 2014;2014:739895.

151) 

Tse AK, Chow KY, Cao HH, Cheng CY,   Kwan HY, Yu H, Zhu GY, Wu YC, Fong WF, Yu ZL (Corresponding Author). The Herbal Compound   Cryptotanshinone Restores Sensitivity in Cancer Cells that are Resistant to   the Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand. J Biol Chem. 2013;288(41):29923-33.

152) 

Ma XQ, Man Leung AK, Chan CL, Su T,   Li WD, Li SM, Fun Fong DW, Yu ZL (Corresponding Author). UHPLC UHD Q-TOF MS/MS   analysis of the impact of sulfur fumigation on the chemical profile of   Codonopsis Radix (Dangshen). Analyst.   2013;139(2):505-16.

153) 

Kwan HY, Hu YM, Chan CL, Cao HH,   Cheng CY, Pan SY, Tse KW, Wu YC, Yu ZL (Corresponding Author), Fong WF. Lipidomics   identification of metabolic biomarkers in chemically induced   hypertriglyceridemic mice. J Proteome   Res. 2013;12(3):1387-98.

154) 

Kwan HY, Yang Z, Fong WF, Hu YM, Yu ZL (Corresponding Author),   Hsiao WL. The anticancer effect of oridonin is mediated by fatty acid   synthase suppression in human colorectal cancer cells. J Gastroenterol. 2013;48(2):182-92.

155) 

Kwan HY, Fong WF, Yang Z, Yu ZL (Corresponding Author),   Hsiao WL. Inhibition of DNA-dependent protein kinase reduced palmitate and   oleate-induced lipid accumulation in HepG2 cells. Eur J Nutr. 2013;52(6):1621-30.

156) 

Su T, Mao C, Yin F, Yu Z, Lin Y, Song Y, Lu T. Effects of   unprocessed versus vinegar-processed Schisandra chinensis on the activity and   mRNA expression of CYP1A2, CYP2E1 and CYP3A4 enzymes in rats. J Ethnopharmacol. 2013;146(3):734-43.

157) 

Pan SY, Jia ZH, Zhang Y, Yu Q, Wang   XY, Sun N, Zhu PL, Yu ZL, Ko KM.   Novel mouse model of combined hyperlipidemia associated with steatosis and   liver injury by a single-dose intragastric administration of schisandrin   B/cholesterol/bile salts mixture. J   Pharmacol Sci. 2013;123(2):110-9.

158) 

Tan Y, Li J, Liu X, Ko J, He X, Lu C,   Liu Z, Zhao H, Xiao C, Niu X, Zha Q, Yu   Z, Zhang W, Lu A. Deciphering the differential toxic responses of Radix   aconiti lateralis praeparata in healthy and hydrocortisone-pretreated rats   based on serum metabolic profiles. J   Proteome Res. 2013;12(1):513-24.

159) 

Pan SY, Yu Q, Zhang Y, Wang XY, Sun   N, Yu ZL, Ko KM. Dietary Fructus   Schisandrae extracts and fenofibrate regulate the serum/hepatic lipid-profile   in normal and hypercholesterolemic mice, with attention to hepatotoxicity. Lipids Health Dis. 2012;11:120.

160) 

Pan SY, Gao SH, Zhou SF, Tang MK, Yu ZL, Ko KM. New perspectives on   complementary and alternative medicine: an overview and alternative therapy. Altern Ther Health Med.   2012;18(4):20-36.

161) 

Huo L, Wu R, Yu   Z, Zhai Y, Yang X, Chan TC, Yeung JT, Kan J, Liang C. The Rix1   (Ipi1p-2p-3p) complex is a critical determinant of DNA replication licensing   independent of their roles in ribosome biogenesis. Cell Cycle. 2012;11(7):1325-39.

162) 

Xu L, Chan CO, Lau CC, Yu Z, Mok DK, Chen S. Simultaneous   determination of eight anthraquinones in Semen Cassiae by HPLC-DAD. Phytochem Anal. 2012;23(2):110-6.

163) 

Tsang TF, Ye Y, Tai WC, Chou GX,   Leung AK, Yu ZL, Hsiao WL.   Inhibition of the p38 and PKA signaling pathways is associated with the   anti-melanogenic activity of Qian-wang-hong-bai-san, a Chinese herbal   formula, in B16 cells. J   Ethnopharmacol. 2012;141(2):622-8.

164) 

Guo D, Xu L, Cao X, Guo Y, Ye Y, Chan   CO, Mok DK, Yu ZL (Corresponding Author),   Chen S. Anti-inflammatory activities and mechanisms of action of the   petroleum ether fraction of Rosa multiflora Thunb. hips. J Ethnopharmacol. 2011;138(3):717-22.

165) 

Chu JH, Wang H, Ye Y, Chan PK, Pan   SY, Fong WF, Yu ZL (Corresponding Author).   Inhibitory effect of schisandrin B on free fatty acid-induced steatosis in   L-02 cells. World J Gastroenterol.   2011;17(19):2379-88.

166) 

Pan SY, Guo BF, Zhang Y, Yu Q, Yu   ZL (Corresponding Author),   Dong H, Ye Y, Han YF, Ko KM. Tacrine treatment at high dose suppresses the   recognition memory in juvenile and adult mice with attention to   hepatotoxicity. Basic Clin Pharmacol   Toxicol. 2011;108(6):421-7.

167) 

Yan Ye, Chou GX, Hui Wang, Chu JH,   Fong WF, Yu ZL (Corresponding Author).   Effects of sesquiterpenes isolated from largehead atractylodes rhizome on   growth, migration, and differentiation of B16 melanoma cells. Integr Cancer Ther.   2011;10(1):92-100.

168) 

Ye Y, Wang H, Chu JH, Chou GX, Chen   SB, Mo H, Fong WF, Yu ZL (Corresponding Author).   Atractylenolide II induces G1 cell-cycle arrest and apoptosis in B16 melanoma   cells. J Ethnopharmacol.   2011;136(1):279-82.

169) 

Ye Y, Wang H, Chu JH, Chou GX, Yu   ZL (Corresponding Author).   Activation of p38 MAPK pathway contributes to the melanogenic property of   apigenin in B16 cells. Exp Dermatol.   2011;20(9):755-7.

170) 

Wang H, Ye Y, Pan SY, Zhu GY, Li YW,   Fong DW, Yu ZL (Corresponding Author).   Proteomic identification of proteins involved in the anticancer activities of   oridonin in HepG2 cells. Phytomedicine.   2011;18(2-3):163-9.

171) 

Wang H, Ye Y, Chu JH, Zhu GY, Fong   WF, Yu ZL (Corresponding Author).   Proteomic and functional analyses reveal the potential involvement of   endoplasmic reticulum stress and α-CP1 in the anticancer activities of   oridonin in HepG2 cells. Integr Cancer   Ther. 2011;10(2):160-7.

172) 

Fang HY, Chen SB, Guo DJ, Pan SY, Yu   ZL (Corresponding Author).   Proteomic identification of differentially expressed proteins in   curcumin-treated MCF-7 cells. Phytomedicine.   2011;18(8-9):697-703.

173) 

Zhu GY, Li YW, Tse AK, Hau DK, Leung   CH, Yu ZL, Fong WF.   20(S)-Protopanaxadiol, a metabolite of ginsenosides, induced cell apoptosis   through endoplasmic reticulum stress in human hepatocarcinoma HepG2 cells. Eur J Pharmacol. 2011;668(1-2):88-98.

174) 

Li YW, Zhu GY, Shen XL, Chu JH, Yu ZL, Fong WF. Furanodienone   inhibits cell proliferation and survival by suppressing ERα signaling in   human breast cancer MCF-7 cells. J   Cell Biochem. 2011;112(1):217-24.

175) 

Li YW, Zhu GY, Shen XL, Chu JH, Yu ZL, Fong WF. Furanodienone induces   cell cycle arrest and apoptosis by suppressing EGFR/HER2 signaling in   HER2-overexpressing human breast cancer cells. Cancer Chemother Pharmacol. 2011;68(5):1315-23.

176) 

Pan SY, Dong H, Guo BF, Zhang Y, Yu ZL, Fong WF, Han YF, Ko KM.   Effective kinetics of schisandrin B on serum/hepatic triglyceride and total   cholesterol levels in mice with and without the influence of fenofibrate. Naunyn Schmiedebergs Arch Pharmacol.   2011;383(6):585-91.

177) 

Pan SY, Chen SB, Dong HG, Yu ZL, Dong JC, Long ZX, Fong WF, Han   YF, Ko KM. New perspectives on chinese herbal medicine (zhong-yao) research   and development. Evid Based Complement   Alternat Med. 2011;2011:403709.

178) 

Hu Y, Yu Z, Yang ZJ, Zhu G, Fong W. Comprehensive chemical analysis of   Venenum Bufonis by using liquid chromatography/electrospray ionization tandem   mass spectrometry. J Pharm Biomed Anal.   2011;56(2):210-20.

179) 

Hu YM, Yu ZL, Fong WF. Stereoselective biotransformation of timosaponin   A-III by Saccharomyces cerevisiae. J   Microbiol Biotechnol. 2011;21(6):582-9.

180) 

Zhu GY, Li YW, Hau DK, Jiang ZH, Yu ZL, Fong WF. Protopanaxatriol-type   ginsenosides from the root of Panax ginseng. J Agric Food Chem. 2011;59(1):200-5.

181) 

Zhu GY, Li YW, Hau DK, Jiang ZH, Yu ZL, Fong WF. Acylated   protopanaxadiol-type ginsenosides from the root of Panax ginseng. Chem Biodivers. 2011;8(10):1853-63.

182) 

Yi T, Chen HB, Zhao ZZ, Yu ZL, Jiang ZH. Comparison of the   chemical profiles and anti-platelet aggregation effects of two "Dragon's   Blood" drugs used in traditional Chinese medicine. J Ethnopharmacol. 2011;133(2):796-802.

183) 

Tse AK, Zhu GY, Wan CK, Shen XL, Yu ZL, Fong WF.   1alpha,25-Dihydroxyvitamin D3 inhibits transcriptional potential of nuclear   factor kappa B in breast cancer cells. Mol   Immunol. 2010;47(9):1728-38.

184) 

Ye Y, Chu JH, Wang H, Xu H, Chou GX,   Leung AK, Fong WF, Yu ZL (Corresponding Author).   Involvement of p38 MAPK signaling pathway in the anti-melanogenic effect of   San-bai-tang, a Chinese herbal formula, in B16 cells. J Ethnopharmacol. 2010;132(2):533-5.

185) 

Ye Y, Chou GX, Mu DD, Wang H, Chu JH,   Leung AK, Fong WF, Yu ZL (Corresponding Author).   Screening of Chinese herbal medicines for antityrosinase activity in a cell   free system and B16 cells. J   Ethnopharmacol. 2010;129(3):387-90.

186) 

Ye Y, Chou GX, Wang H, Chu JH, Yu ZL (Corresponding Author).   Flavonoids, apigenin and icariin exert potent melanogenic activities in   murine B16 melanoma cells. Phytomedicine.   2010 Dec 15;18(1):32-5.

187) 

Wang H, Chan PK, Pan SY, Kwon KH, Ye Y, Chu JH,   Fong WF, Tsui WM, Yu ZL (Corresponding Author).   ERp57 is up-regulated in free fatty acids-induced steatotic L-02 cells and   human nonalcoholic fatty livers. J   Cell Biochem. 2010;110(6):1447-56.

188) 

Wang H, Ye Y, Chui JH, Zhu GY, Li YW,   Fong DW, Yu ZL (Corresponding Author).   Oridonin induces G2/M cell cycle arrest and apoptosis through MAPK and p53   signaling pathways in HepG2 cells. Oncol   Rep. 2010;24(3):647-51.